Multisociety sepsis position paper, trauma nutrition protocol, and two definitions of heart failure that disagree

Three genuinely new guidelines, plus the Second Universal Definition of Heart Failure — which sits awkwardly against yesterday's ESC guidelines.

Nothing new from the French societies since yesterday’s check (SFAR, SRLF, SPILF). ESC Congress continues through 31 August; yesterday’s ESC heart failure guidelines and Fifth Universal Definition of MI are in the 28 August entry.

1. Multisociety position paper — hospital strategies to improve sepsis outcomes

Society · Published: IDSA, convening ACEP, ASM, PIDS, SCCM, SHEA, SHM and SIDP. Clinical Infectious Diseases, 25 August 2026genuinely new, 4 days old Rhee, Masur, Klompas et al.

The stated gap: CMS and CDC are advancing new sepsis quality measures focused on outcomes and hospital programmatic capacity, and the Surviving Sepsis Campaign covers bedside management — but nothing addresses hospital-based strategy across the continuum of care. This fills that, focused on the infection-related aspects, across six domains: diagnostic testing and pathogen detection, antimicrobial management and delivery, surveillance and performance metrics, adjunctive therapy, program infrastructure and organisational support, and infection prevention.

Concrete examples the panel gives:

  • Multiplex nucleic acid amplification testing on positive blood cultures, paired with active stewardship support
  • Optimising workflows for timely antibiotic delivery in septic shock
  • Clinical decision support to prioritise β-lactam administration before vancomycin when both are ordered
  • Defaulting antipseudomonal β-lactams to prolonged infusion in critically ill patients
  • EHR-based sepsis surveillance
  • Tracking rates of inadequate empiric therapy, unnecessarily broad empiric therapy, antibiotic de-escalation, and timeliness of source control

Interpretation. The β-lactam-before-vancomycin recommendation is the one to act on tomorrow: it costs nothing, it is a pure ordering problem, and it addresses a real delay that nobody designed and everybody tolerates. Prolonged-infusion β-lactams as the default rather than an option is the other substantive shift, and it aligns with the Hong et al. prolonged-infusion paper noted on 25 August.

Read the framing as a deliberate move away from SEP-1. That measure drove broad-spectrum antibiotics and fluid bundles regardless of phenotype, and the criticism — much of it from Rhee and Klompas themselves — was that it optimised documentation rather than care. This paper’s metrics are notably about appropriateness (inadequate empiric therapy, unnecessarily broad therapy, de-escalation) rather than speed alone. That is the argument being won in public.

Read the position paper · PMID 42640090

2. AAST/ACS clinical protocol — nutrition support in adult trauma

Society · Published: American Association for the Surgery of Trauma with the ACS Committee on Trauma. Journal of Trauma and Acute Care Surgery, 26 August 2026genuinely new, 3 days old Valenzuela, Haines, Sachdev, Napolitano et al.

  • Assess every patient for malnutrition — the hypermetabolic state of acute trauma can worsen malnutrition risk during the acute phase
  • ICU patients: determine nutrition risk (high vs low) with modified NUTRIC or NRS, and evaluate for malnutrition
  • Indirect calorimetry is most accurate for calorie and protein requirements in the critically ill
  • Early enteral nutrition once resuscitation is complete; continuous gastric feeds, with postpyloric jejunal feeding where aspiration risk is high
  • Feeding intolerance and ileus: prokinetics first, then a postpyloric tube if intolerance persists
  • Parenteral nutrition if enteral is contraindicated (obstruction, severe ileus, high-output fistula, ischaemia) or goal enteral cannot be reached
  • Shock on vasopressors: individualised, weighing early enteral nutrition against the risk of non-occlusive mesenteric ischaemia
  • Geriatric, obese and cirrhotic trauma patients warrant specialised care
  • Immunonutrition, glutamine and probiotics/prebiotics are not recommended for trauma or burn patients

Graded Level V, therapeutic/care management.

Interpretation. The negative recommendations carry the most weight. Glutamine has been formally dead since REDOXS (NEJM 2013) showed increased mortality, yet it persists in protocols; immunonutrition has been fading since the sepsis signal in the 2000s. Seeing all three named and excluded in one line is useful for anyone still maintaining a local formulary.

The vasopressor paragraph is the honest one — it declines to give a rule, which is right, because the evidence for early enteral nutrition in shock (NUTRIREA-2 and NUTRIREA-3) points at harm in the sickest without defining a threshold. Note this is Level V evidence throughout: a protocol built on expert consensus, not trials.

Read the protocol · PMID 42647750

3. Empyema and chylothorax — management algorithm

Society · Published: Journal of Trauma and Acute Care Surgery Emergency General Surgery Algorithms work group, 24 August 2026genuinely new, 5 days old Winchell, Biffl, Costantini, Diaz, Inaba, Livingston, Martin, Napolitano, Salim et al.

Access note: no abstract is deposited for this one, and the full text was not reachable. Recorded here as a pointer, not summarised — I have not seen the algorithm’s content and will not guess at it.

Directly relevant to thoracic surgical practice, and worth retrieving if empyema management is a live question in your unit. The Emergency General Surgery Algorithms series is deliberately practical and cost-conscious in framing.

Article page · PMID 42635972

4. Second Universal Definition of Heart Failure (2026)

Society · Published: AHA, ACC, ESC and WHF, with HFSA, HFA and JHFS. Circulation and JACC, ~June 2026~3 months old, appearing now in the European Heart Journal print issue, which is why the aggregator surfaced it today.

  • Moves away from rigid LVEF cutoffs, grouping heart failure into reduced, preserved and improved ejection fraction
  • Reaffirms the four stages — A at risk, B pre-heart failure, C heart failure, D advanced — and centres Stage B as the critical window for early detection, monitoring and proactive individualised intervention
  • Adds a universal classification by cause, to standardise how aetiology is reported in practice and research
  • Addresses dynamic trajectories — improvement, remission, recovery — and the effect of social determinants and geographic variation

Interpretation, and a genuine tension worth noticing. Yesterday’s 2026 ESC heart failure guidelines collapsed the phenotypes to two, defined by a hard cutoff: HFrEF below 50%, HFpEF at or above 50%. This document, which ESC co-authored, explicitly moves away from rigid cutoffs and keeps a three-way grouping that includes improved EF — a category the ESC scheme has no place for.

Both are current, both carry ESC’s name, and they classify the same patients differently. The improved-EF group is the substantive disagreement: a patient whose EF recovers from 30% to 55% is HFpEF under the ESC guideline and HFimpEF under the universal definition, and those labels imply different things about whether to continue therapy. Worth watching how this gets reconciled — and worth being precise about which document you are citing when it matters.

Circulation · JACC · PMID 42366993

5. Cardiac ultrasound in cardiovascular emergency and critical care

Society · Published: European Association of Cardiovascular Imaging, the Acute CardioVascular Care Association, and the European Association of Cardiothoracic Anaesthesia and Intensive Care (EACTAIC). EHJ Cardiovascular Imaging, 1 October 2025~11 months old, not new. The aggregator listed it today; the listing date is not the publication date. Soliman Aboumarie, Tavazzi, Via, Guarracino, Stankovic, Hagendorff, Gargani et al.

No abstract is deposited, so this is recorded as a pointer rather than summarised.

Included despite its age because it has never been surfaced here and EACTAIC is a directly relevant co-author — this is the cardiothoracic anaesthesia and intensive care community’s own consensus on echo in the emergency and critical care setting, with Guarracino and Tavazzi among the authors.

Article page · PMID 40838793